Recent development of near-infrared photoacoustic probes based on small-molecule organic dye
Chonglu Li, Chang Liu, Yifan Fan, Xin Ma, Yibei Zhan, Xiaoju Lu, Yao Sun
Abstract
features and facile functionalization. In recent years, PAI, in the near-infrared region (NIR, 700-1700 nm) has developed rapidly and has made remarkable achievements in the biomedical field. Compared with the visible light region (400-700 nm), it can significantly reduce light scattering and meanwhile provide deeper tissue penetration. In this review, we discuss the recent developments of near-infrared photoacoustic probes based on small molecule dyes, which focus on their "always on" and "activatable" form in biomedicine. Further, we also suggest current challenges and perspectives.
Topics & Concepts
Photoacoustic imaging in biomedicineMaterials scienceNanotechnologyPenetration (warfare)InfraredPenetration depthOrganic moleculesSurface modificationMoleculeOpticsChemistryOrganic chemistryOperations researchPhysical chemistryPhysicsEngineeringNanoplatforms for cancer theranosticsPhotoacoustic and Ultrasonic ImagingLuminescence and Fluorescent Materials