Charge-reversal nanocomolexes-based CRISPR/Cas9 delivery system for loss-of-function oncogene editing in hepatocellular carcinoma
Jing‐Jun Nie, Yanli Liu, Qi Yu, Nasha Zhang, Bingran Yu, Dafu Chen, Ming Yang, Fu‐Jian Xu
Topics & Concepts
Hepatocellular carcinomaCRISPRCancer researchOncogeneSorafenibCas9SurvivinApoptosisDelivery systemCancerMedicineAngiogenesisTargeted therapyLiver cancerBiologyPharmacologyInternal medicineBiochemistryCell cycleGeneCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery