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Radiotherapy-mediated redox homeostasis-controllable nanomedicine for enhanced ferroptosis sensitivity in tumor therapy

Lin Yang, Xiangwu Chen, Cancan Yu, Guixiang Xu, Xinxin Nie, Yufeng Cheng, Yuxia Luan, Qingxu Song

2023Acta Biomaterialia99 citationsDOI

Topics & Concepts

NanomedicineReactive oxygen speciesThioredoxinCancer researchTumor microenvironmentGPX4AntioxidantGlutathioneChemistryCell biologyRadiation therapyHomeostasisCancer cellOxidative stressCancerBiologyBiochemistryMedicineMaterials scienceNanotechnologyGlutathione peroxidaseSuperoxide dismutaseTumor cellsInternal medicineEnzymeNanoparticleFerroptosis and cancer prognosisNanoplatforms for cancer theranosticsHeme Oxygenase-1 and Carbon Monoxide
Radiotherapy-mediated redox homeostasis-controllable nanomedicine for enhanced ferroptosis sensitivity in tumor therapy | Litcius