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Infection with SARS-CoV-2 in primary care health care workers assessed by antibody testing

Korbinian Lackermair, Frederic William, Noelle Grzanna, Elke Lehmann, Stephanie Fichtner, Hans Bernd Kucher, Karl Wilhelm, Heidi Estner

2020Family Practice27 citationsDOIOpen Access PDF

Abstract

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a pandemic threat of public health during the last month causing more than 10 million infections and 500 000 deceased patients worldwide. Nevertheless, data about risk of infection for health care workers are sparse. METHODS: In a large primary care facility, 151 workers underwent SARS-CoV-2 immunoglobulin G (IgG) testing. In addition, participants had to complete a survey regarding symptoms and their individual risk of infection. RESULTS: Symptoms suspicious for COVID-19 occurred in 72%, fever in 25% of all subjects. Four workers (2.6%, 95% confidence interval 0.8-7.1%) had a positive SARS-CoV-2 antibody testing. None of these was free from COVID-19 suspicious symptoms. Source of infection was presumably professional in three of four individuals. CONCLUSION: Our systematic analysis of SARS-CoV-2 infection in a cohort of health care workers in a large outpatient centre revealed an apparently low rate of 2.6% past SARS-CoV-2 infections. Relative risk for infection following health care profession cannot be derived as data about infection rates in the corresponding general population are lacking.

Topics & Concepts

MedicineConfidence intervalHealth carePopulationPandemicCohortPublic healthRisk of infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Cohort studyEmergency medicineCoronavirus disease 2019 (COVID-19)Internal medicineEnvironmental healthDiseaseInfectious disease (medical specialty)PathologyGeneticsEconomicsEconomic growthBiologySARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesSARS-CoV-2 detection and testing
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