Effect of Exercise and Quercetin in Rats with Metabolic Syndrome Induced with Fructose.
Fatmanur Er, Erdal Zorba, Mehmet Günay, Mitat Koz, Canan Yılmaz, Özge Tuğçe Paşaoğlu, Nurten Türközkan
Abstract
These results show that high fructose consumption leads to elevated SBP, TG, cholesterol, body fat mass, glucose, insulin, and HOMA-IR levels, and aerobic exercise training treatment has beneficial effects on these biochemical parameters in rats. Although quercetin has positive effects on SBP and insulin levels, it was observed to cause a significant increase especially in TG and body fat mass. Therefore, more detailed dose studies and pathways of quercetin are needed to elucidate its mechanism of action in body fat mass.
Topics & Concepts
FructoseMedicineInternal medicineInsulin resistanceEndocrinologyMetabolic syndromeQuercetinHomeostatic model assessmentInsulinBody mass indexObesityChemistryBiochemistryAntioxidantDiet, Metabolism, and DiseaseLiver Disease Diagnosis and TreatmentDiet and metabolism studies