NIR-II cell endocytosis-activated fluorescent probes for <i>in vivo</i> high-contrast bioimaging diagnostics
Yue He, Shangfeng Wang, Peng Yu, Kui Yan, Ming Jiang, Chenzhi Yao, Zuyang He, Ahmed Mohamed El‐Toni, Aslam Khan, Xinyan Zhu, Caixia Sun, Zuhai Lei, Fan Zhang
Abstract
imaging of tumor and inflammation with a passive-targeting and affinity-tagged CEAF probe, respectively, yields highly specific signals with target-to-background ratios over 15 and prolonged observation time up to 35 hours, enabling positive implications for surgical, diagnostic and fundamental biomedical studies.
Topics & Concepts
EndocytosisFluorescenceIn vivoContrast (vision)ChemistryCellBiophysicsNanotechnologyMaterials scienceBiochemistryBiologyComputer sciencePhysicsOpticsGeneticsArtificial intelligenceNanoplatforms for cancer theranosticsPhotoreceptor and optogenetics researchMolecular Sensors and Ion Detection