Polysaccharide from Schisandra chinensis acts via LRP-1 to reverse microglia activation through suppression of the NF-κB and MAPK signaling
Mengjie Xu, Jinyu Wang, Xiaoying Zhang, Tingxu Yan, Bo Wu, Kaishun Bi, Ying Jia
Topics & Concepts
MAPK/ERK pathwaySchisandra chinensisNeuroinflammationNeuroprotectionMicrogliaSignal transductionBiologyIκBαChemistryMolecular biologyPharmacologyCell biologyNF-κBImmunologyMedicineInflammationAlternative medicinePathologyTraditional Chinese medicinePlant-derived Lignans Synthesis and BioactivityNeuroinflammation and Neurodegeneration MechanismsPolysaccharides and Plant Cell Walls