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Evaluation of the accuracy and safety of machine translation of patient-specific discharge instructions: a comparative analysis

Marianna Kong, Alicia Fernández, Jaskaran Bains, Ana Milisavljevic, Katherine C. Brooks, Akash Shanmugam, Leslie Avilez, Junhong Li, Vlad Honcharov, Andersen Yang, Elaine C. Khoong

2025BMJ Quality & Safety19 citationsDOIOpen Access PDF

Abstract

INTRODUCTION: Machine translation of patient-specific information could mitigate language barriers if sufficiently accurate and non-harmful and may be particularly useful in healthcare encounters when professional translators are not readily available. We evaluated the translation accuracy and potential for harm of ChatGPT-4 and Google Translate in translating from English to Spanish, Chinese and Russian. METHODS: We used ChatGPT-4 and Google Translate to translate 50 sets (316 sentences) of deidentified, patient-specific, clinician free-text emergency department instructions into Spanish, Chinese and Russian. These were then back-translated into English by professional translators and double-coded by physicians for accuracy and potential for clinical harm. RESULTS: At the sentence level, we found that both tools were ≥90% accurate in translating English to Spanish (accuracy: GPT 97%, Google Translate 96%) and English to Chinese (accuracy: GPT 95%; Google Translate 90%); neither tool performed as well in translating English to Russian (accuracy: GPT 89%; Google Translate 80%). At the instruction set level, 16%, 24% and 56% of Spanish, Chinese and Russian GPT-translated instruction sets contained at least one inaccuracy. For Google Translate, 24%, 56% and 66% of Spanish, Chinese and Russian translations contained at least one inaccuracy. The potential for harm due to inaccurate translations was ≤1% for both tools in all languages at the sentence level and ≤6% at the instruction set level. GPT was significantly more accurate than Google Translate in Chinese and Russian at the sentence level; the potential for harm was similar. CONCLUSION: These results support the potential of machine translation tools to mitigate gaps in translation services for low-stakes written communication from English to Spanish, while also strengthening the case for caution and for professional oversight in non-low-risk communication. Further research is needed to evaluate machine translation for other languages and more technical content.

Topics & Concepts

HarmSentenceMachine translationSet (abstract data type)Natural language processingComputer scienceArtificial intelligenceHealth carePatient safetyMedicinePsychologyPolitical scienceSocial psychologyProgramming languageLawArtificial Intelligence in Healthcare and EducationInterpreting and Communication in HealthcareElectronic Health Records Systems
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