HDAC and MAPK/ERK Inhibitors Cooperate To Reduce Viability and Stemness in Medulloblastoma
Mariane da Cunha Jaeger, Eduarda Chiesa Ghisleni, Paula Schoproni Cardoso, Marialva Siniglaglia, Tiago Falcón, André T. Brunetto, Algemir Lunardi Brunetto, Caroline Brunetto de Farias, Michael D. Taylor, Carolina Nör, Vijay Ramaswamy, Rafael Roesler
Topics & Concepts
MAPK/ERK pathwayHomeobox protein NANOGBMI1Cancer stem cellBiologyCancer researchHistone deacetylaseNeurosphereSOX2Stem cellNeural stem cellRHOAEmbryonic stem cellCell biologySignal transductionHistoneBiochemistryAdult stem cellInduced pluripotent stem cellGeneHistone Deacetylase Inhibitors ResearchGlioma Diagnosis and TreatmentEpigenetics and DNA Methylation