Imiquimod-induced ROS production causes lysosomal membrane permeabilization and activates caspase-8-mediated apoptosis in skin cancer cells
Shu-Hao Chang, Pei-Ying Lin, Tsai-Kun Wu, Chien‐Sheng Hsu, Shi‐Wei Huang, Zhengyi Li, Kuang-Ting Liu, Jun‐Kai Kao, Yi–Ju Chen, Tak‐Wah Wong, Chun‐Ying Wu, Jeng‐Jer Shieh
Topics & Concepts
LysosomeApoptosisProgrammed cell deathCell biologyCaspaseCathepsinFlow cytometryCancer cellBiologyCell cultureCancer researchChemistryMolecular biologyCancerBiochemistryEnzymeGeneticsCell death mechanisms and regulationAutophagy in Disease and TherapyRetinoids in leukemia and cellular processes