Pyridylidene Amide Ru Complex for Selective Oxidation in Organic Synthesis
Simone Bertini, Dorothée Henryon, Andrew Edmunds, Martin Albrecht
Abstract
The ruthenium(II) bis(PYA) complex 1 (PYA = p-pyridylidene amide) is a powerful catalyst for the oxidation of sulfides to sulfones, of alkenes to carbonyl compounds, and of terminal alkynes to carboxylic acids by using NaIO4 as the terminal oxidant. The catalytic system shows a broad functional group tolerance and rate differences between alkyne and sulfide oxidation that are sufficiently large to effectively achieve selective sulfide oxidation with exquisite selectivity.
Topics & Concepts
ChemistryAmideSulfideCatalysisSelectivityRutheniumAlkyneFunctional groupCombinatorial chemistryOrganic chemistryPolymerOxidative Organic Chemistry ReactionsChemical Synthesis and ReactionsSulfur-Based Synthesis Techniques