Use of an Integrated Multi-Omics Approach To Identify Molecular Mechanisms and Critical Factors Involved in the Pathogenesis of <i>Leptospira</i>
Sridhar Kavela, Pallavi Vyas, Jusail CP, Sandeep Kushwaha, Subeer S. Majumdar, Syed M. Faisal
Abstract
with human macrophages and identifies a few critical factors (such as virulence-associated proteins) involved in pathogenesis. These factors can be exploited for the development of novel tools for the detection, treatment, or prevention of leptospirosis.
Topics & Concepts
LeptospiraBiologyLeptospira interrogansTranscriptomeVirulencePathogenesisEffectorInnate immune systemMicrobiologyVirulence factorGeneGeneticsComputational biologyImmune systemCell biologyGene expressionSerotypeImmunologyLeptospirosis research and findingsViral Infections and VectorsVeterinary medicine and infectious diseases