<i>In Vitro</i> and <i>In Vivo</i> Efficacy of Albendazole Chitosan Microspheres with Intensity-Modulated Radiation Therapy in the Treatment of Spinal Echinococcosis
Sibo Wang, Shan Wang, Weishan Wang, Yi Dai, Zhongpeng Qiu, Wei Ke, Minghao Geng, Jing Li, Ke Li, Qingyuan Ma, Feng Li
Abstract
Currently, there is a lack of clinically safe and effective treatment for spinal cystic echinococcosis (CE). Recent studies have shown that albendazole chitosan microspheres (ABZ-CS-MPs) and irradiation have certain anti-abdominal echinococcosis ability, so this study aims to compare the in vitro and in vivo therapeutic effects of ABZ-CS-MPs, intensity-modulated radiation therapy (IMRT), and combination therapy on spinal echinococcosis.
Topics & Concepts
AlbendazoleMicrosphereIn vivoIn vitroAnthelminticChitosanMedicinePharmacologyEchinococcosisChemistryPathologySurgeryBiologyVeterinary medicineBiotechnologyBiochemistryEngineeringChemical engineeringParasitic infections in humans and animalsParasitic Infections and DiagnosticsCongenital Anomalies and Fetal Surgery