Introduction of Lipophilic Side Chains to <i>N</i>H-Sulfoximines by Palladium Catalysis Under Blue Light Irradiation
Ding Ma, Deshen Kong, Peng Wu, Yongliang Tu, Peng Shi, Xianliang Wang, Carsten Bolm
Abstract
Palladium catalysis under blue (LED) light irradiation allows conversion of NH-sulfoximines into products with long lipophilic side chains attached to the S═N moiety. The three-component reactions involve both radicals and organometallic intermediates stemming from alkyl bromides and butadienes. The substrate scope is broad, and the products are formed in moderate to good yields.
Topics & Concepts
ChemistryPalladiumCatalysisMoietyAlkylRadicalIrradiationSubstrate (aquarium)Side chainBlue lightPhotochemistryOrganic chemistryCombinatorial chemistryPolymerGeologyPhysicsNuclear physicsOpticsOceanographySynthesis and Catalytic ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques