Demethylase JMJD2D induces PD-L1 expression to promote colorectal cancer immune escape by enhancing IFNGR1-STAT3-IRF1 signaling
Qiang Chen, Shuqing Zhuang, Yilin Hong, Lingtao Yang, Peng Guo, Pingli Mo, Kesong Peng, Wengang Li, Nengming Xiao, Chundong Yu
Topics & Concepts
BiologyCancer researchPD-L1Immune systemCD8Cancer cellCancer immunotherapyIRF1Tumor microenvironmentT cellColorectal cancerImmunotherapyCancerTranscription factorImmunologyBiochemistryGeneGeneticsCancer Immunotherapy and BiomarkersImmune cells in cancerFerroptosis and cancer prognosis