Diastereoselective Rhodium-Catalyzed Hydrogenation of 2-Oxindoles and 3,4-Dihydroquinolones
Christian H. Schiwek, Christian Jandl, Thorsten Bach
Abstract
arrangement. The high tolerance toward functional groups and the compatibility with existing stereogenic centers are key features of the hydrogenation protocol presented here.
Topics & Concepts
ChemistryStereocenterSubstituentRhodiumCyclohexaneRing (chemistry)BenzeneStereoselectivityYield (engineering)Medicinal chemistryDiastereomerCatalysisStereochemistryOrganic chemistryEnantioselective synthesisMetallurgyMaterials scienceAsymmetric Hydrogenation and CatalysisCatalytic C–H Functionalization MethodsAsymmetric Synthesis and Catalysis