Solvent Drives Switching between Λ and Δ Metal Center Stereochemistry of M<sub>8</sub>L<sub>6</sub> Cubic Cages
Weichao Xue, Tanya K. Ronson, Zifei Lu, Jonathan R. Nitschke
Abstract
, in nitromethane. Van 't Hoff analysis revealed the Δ stereochemical configuration to be entropically favored but enthalpically disfavored, consistent with a loosening of the coordination sphere and an increase in conformational freedom following Λ-to-Δ transition. The binding of 4,4'-dipyridyl naphthalenediimide and tetrapyridyl Zn-porphyrin guests did not interfere with the solvent-driven stereoselectivity of self-assembly, suggesting applications where either a Λ- or Δ-handed framework may enable chiral separations or catalysis.
Topics & Concepts
ChemistryStereocenterEnantiopure drugLigand (biochemistry)NitromethaneStereochemistryChirality (physics)MetalDenticityDiastereomerCrystallographyAcetonitrileCoordination sphereSolventOctahedronCatalysisCrystal structureEnantioselective synthesisOrganic chemistryQuarkBiochemistryPhysicsNambu–Jona-Lasinio modelQuantum mechanicsReceptorChiral symmetry breakingSupramolecular Chemistry and ComplexesMetal-Organic Frameworks: Synthesis and ApplicationsMagnetism in coordination complexes