Linear-Organic-Polymer-Supported Iridium Complex as a Recyclable Auto-Tandem Catalyst for the Synthesis of Quinazolinones via Selective Hydration/Acceptorless Dehydrogenative Coupling from <i>o</i>-Aminobenzonitriles
Shushu Hao, Jiazhi Yang, Peng Liu, Jing Xu, Chenchen Yang, Feng Li
Abstract
A linear-organic-polymer-supported iridium complex Cp*Ir@P4VP, which is designed and synthesized by the coordinative immobilization of [Cp*IrCl2]2 on poly(4-vinylpyridine), was proven to be an efficient heterogeneous autotandem catalyst for synthesizing quinazolinones via selective hydration/acceptorless dehydrogenative coupling from o-aminobenzonitriles. Furthermore, the synthesized catalyst was recycled five times without an obvious decrease in the catalytic activity.
Topics & Concepts
IridiumCatalysisChemistryTandemCombinatorial chemistryPolymerCoupling (piping)Chemical engineeringOrganic chemistryMaterials scienceMetallurgyEngineeringComposite materialQuinazolinone synthesis and applicationsAsymmetric Hydrogenation and CatalysisSynthesis and Biological Evaluation