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Targeting ABCB6 with nitidine chloride inhibits PI3K/AKT signaling pathway to promote ferroptosis in multiple myeloma

Zhao Yin, Yiwen Lv, Deng Li, Guangchao Li, Ruiming Ou, Lizhi Chen, Yangmin Zhu, Qi Zhong, Zhi Liu, Jing Huang, Hong Wu, Qing Zhang, Jia Fei, Jia Fei, Shuang Liu

2023Free Radical Biology and Medicine41 citationsDOI

Topics & Concepts

ChemistryPI3K/AKT/mTOR pathwayProtein kinase BMolecular biologyFlow cytometryWestern blotCancer researchApoptosisBiologyBiochemistryGeneDrug Transport and Resistance MechanismsCancer Mechanisms and TherapyFerroptosis and cancer prognosis
Targeting ABCB6 with nitidine chloride inhibits PI3K/AKT signaling pathway to promote ferroptosis in multiple myeloma | Litcius