An anticancer Ti(IV) complex increases mitochondrial reactive oxygen species levels in relation with hypoxia and endoplasmic-reticulum stress: A distinct non DNA-related mechanism
Zohar Shpilt, Naomi Melamed‐Book, Edit Y. Tshuva
Topics & Concepts
Reactive oxygen speciesChemistryOxidative stressHeLaCytotoxicityCisplatinMitochondrionMitochondrial ROSApoptosisCell biologyGlutathioneEndoplasmic reticulumCellBiophysicsBiochemistryBiologyIn vitroChemotherapyEnzymeGeneticsLanthanide and Transition Metal ComplexesMetal complexes synthesis and propertiesNanoparticle-Based Drug Delivery