Fungal Infections in Liver Transplant Recipients
Michael Scolarici, Margaret R. Jorgenson, Christopher M. Saddler, Jeannina A. Smith
Abstract
Invasive fungal infections (IFIs) are one of the most feared complications associated with liver transplantation, with high rates of morbidity and mortality. We discuss the most common invasive fungal infections in the setting of liver transplant, including Candida, Aspergillus, and Cryptococcal infections, and some less frequent but devastating mold infections. Further, we evaluate the use of prophylaxis to prevent invasive fungal infection in this population as a promising mechanism to reduce risks to patients after liver transplant.
Topics & Concepts
Liver transplantationAspergillusAspergillosisMedicinePopulationIntensive care medicineBiologyImmunologyTransplantationInternal medicineMicrobiologyEnvironmental healthAntifungal resistance and susceptibilityFungal Infections and StudiesPneumocystis jirovecii pneumonia detection and treatment