A numerical study on drug delivery<i>via</i>multiscale synergy of cellular hitchhiking onto red blood cells
Mehdi Nikfar, Meghdad Razizadeh, Ratul Paul, Vladimir R. Muzykantov, Yaling Liu
Abstract
Red blood cell (RBC)-hitchhiking, in which different nanocarriers (NCs) shuttle on the erythrocyte membrane and disassociate from RBCs to the first organ downstream of the intravenous injection spot, has recently been introduced as a solution to enhance target site uptake.
Topics & Concepts
Drug deliveryDrugNanotechnologyComputer scienceChemistryMaterials sciencePharmacologyMedicineErythrocyte Function and PathophysiologyPhagocytosis and Immune RegulationLipid Membrane Structure and Behavior