Modulation of chondroprotective hyaluronic acid and poloxamer gel with Ketoprofen loaded transethosomes: Quality by design-based optimization, characterization, and preclinical investigations in osteoarthritis
Aishwarya Mammella, Valamla Bhavana, Padakanti Sandeep Chary, Urati Anuradha, Neelesh Kumar Mehra
Topics & Concepts
Hyaluronic acidKetoprofenPoloxamerOsteoarthritisPoloxamer 407ChemistryQuality by DesignModulation (music)PharmacologyChromatographyBiomedical engineeringPolymerMedicineOrganic chemistryParticle sizePhilosophyAnatomyPathologyAestheticsAlternative medicinePhysical chemistryCopolymerOsteoarthritis Treatment and MechanismsInflammatory mediators and NSAID effectsProteoglycans and glycosaminoglycans research