Contribution of DNA methyltransferases to spared nerve injury induced depression partially through epigenetically repressing Bdnf in hippocampus: Reversal by ketamine
Ru Liu, Xin‐miao Wu, Xue He, Run-zhu Wang, Xiaoyu Yin, Feng Zhou, Mu‐Huo Ji, Jin-Chun Shen
Topics & Concepts
Brain-derived neurotrophic factorHippocampusNeurotrophic factorsTPH2SNiKetamineNeuropathic painMedicineNerve injuryDNA methylationMethyltransferaseInternal medicineEndocrinologyPsychologyAnesthesiaMethylationBiologyGene expressionSerotoninSerotonergicReceptorGeneticsAcid hydrolysisBiochemistryHydrolysisGeneTryptophan and brain disordersPain Mechanisms and TreatmentsTreatment of Major Depression