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Blocking PD-1/PD-L1 by an ADCC enhanced anti-B7-H3/PD-1 fusion protein engages immune activation and cytotoxicity

Yao Xu, Yang Xiao, Cheng Luo, Qingxia Liu, Aiqi Wei, Yang Yang, Liwen Zhao, Yong Wang

2020International Immunopharmacology19 citationsDOI

Topics & Concepts

Antibody-dependent cell-mediated cytotoxicityFusion proteinImmune systemCancer researchChemistryAntibodyMonoclonal antibodyBiologyImmunologyBiochemistryRecombinant DNAGeneCAR-T cell therapy researchMonoclonal and Polyclonal Antibodies ResearchImmunotherapy and Immune Responses
Blocking PD-1/PD-L1 by an ADCC enhanced anti-B7-H3/PD-1 fusion protein engages immune activation and cytotoxicity | Litcius