2AB protein of Senecavirus A antagonizes selective autophagy and type I interferon production by degrading LC3 and MARCHF8
Dage Sun, Ning Kong, Sujie Dong, Xiaoyong Chen, Wenzhen Qin, Hua Wang, Yajuan Jiao, Huanjie Zhai, Liwei Li, Fei Gao, Lingxue Yu, Hao Zheng, Tong Wu, Hai Yu, Wen Zhang, Guangzhi Tong, Tongling Shan
Abstract
: 50% tissue culture infectious doses.
Topics & Concepts
AutophagyBiologyCell biologyInterferonBafilomycinImmunoprecipitationViral proteinBAG3Viral replicationVirologyVirusGeneGeneticsApoptosisAutophagy in Disease and TherapyAnimal Disease Management and EpidemiologyViral Infections and Vectors