Development of the Peritoneal Metastasis: A Review of Back-Grounds, Mechanisms, Treatments and Prospects
Kaijie Ren, Xin Xie, Tianhao Min, Tuanhe Sun, Haonan Wang, Yong Zhang, Chengxue Dang, Hao Zhang
Abstract
Peritoneal metastasis is a malignant disease which originated from several gastrointestinal and gynecological carcinomas and has been leading to a suffering condition in patients for decades. Currently, as people have gradually become more aware of the severity of peritoneal carcinomatosis, new molecular mechanisms for targeting and new treatments have been proposed. However, due to the uncertainty of influencing factors involved and a lack of a standardized procedure for this treatment, as well as a need for more clinical data for specific evaluation, more research is needed, both for preventing and treating. We aim to summarize backgrounds, mechanisms and treatments in this area and conclude limitations or new aspects for treatments.