FMO3 exacerbates hepatic endoplasmic reticulum stress in drug-induced liver injury by inhibiting CREB3/P4HB axis and activating TMAO-mediated PERK pathway
Han Zhang, Si Zhao, Rui Fang, Xue Wang, Huan Chen, Zihao Cai, Yan Liu, Jingjing Tu, Feng Zhang, Wei Zhang, Ming Zhang, Bing Xu, Yuzheng Zhuge, Jiangqiang Xiao
Topics & Concepts
Endoplasmic reticulumUnfolded protein responseDrugLiver injuryPharmacologyChemistryMedicineInternal medicineEndocrinologyCell biologyBiologyBiochemistryDrug-Induced Hepatotoxicity and ProtectionAlcohol Consumption and Health EffectsBerberine and alkaloids research