Fabrication, Optimization, and Evaluation of Paclitaxel and Curcumin Coloaded PLGA Nanoparticles for Improved Antitumor Activity
Haiyang Hu, Zuyue Liao, Mengyao Xu, Shengli Wan, Yuesong Wu, Wenjun Zou, Jianming Wu, Qingze Fan
Abstract
values to 4T1 and MCF-7 breast cancer cell lines compared to free drugs. In summary, BBD optimization of CUR and PTX coloaded nanoparticles yielded a favorable drug carrier that holds potential as an alternative treatment for anticancer therapy.
Topics & Concepts
PLGAPaclitaxelNanoparticleCurcuminPulmonary surfactantNanotechnologyMaterials scienceDrug deliveryChemistryPharmacologyCancerBiochemistryMedicineInternal medicineNanoparticle-Based Drug DeliveryAdvanced Drug Delivery SystemsDendrimers and Hyperbranched Polymers