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Real-World Issues and Potential Solutions in Hematopoietic Cell Transplantation during the COVID-19 Pandemic: Perspectives from the Worldwide Network for Blood and Marrow Transplantation and Center for International Blood and Marrow Transplant Research Health Services and International Studies Committee

Ghada Algwaiz, Mahmoud Aljurf, Mickey Koh, Mary M. Horowitz, Per Ljungman, Daniel J. Weisdorf, Wael Saber, Yoshihisa Kodera, Jeff Szer, Dunia Jawdat, William A. Wood, Ruta Brazauskas, Leslie Lehmann, Marcelo C. Pasquini, Adriana Seber, Pei Lü, Yoshiko Atsuta, Marcie Riches, Miguel‐Angel Perales, Nina Worel, Shinichiro Okamoto, Alok Srivastava, Roy F. Chemaly, Catherine Cordonnier, Christopher E. Dandoy, John R. Wingard, Mohamed A. Kharfan‐Dabaja, Mehdi Hamadani, Navneet S. Majhail, Alpana Waghmare, Nelson J. Chao, Nicolaus Kröger, Bronwen E. Shaw, Mohamad Mohty, Dietger Niederwieser, Hildegard Greinix, Shahrukh K. Hashmi

2020Biology of Blood and Marrow Transplantation61 citationsDOIOpen Access PDF

Abstract

The current COVID-19 pandemic, caused by SARS-CoV-2, has impacted many facets of hematopoietic cell transplantation (HCT) in both developed and developing countries. Realizing the challenges as a result of this pandemic affecting the daily practice of the HCT centers and the recognition of the variability in practice worldwide, the Worldwide Network for Blood and Marrow Transplantation (WBMT) and the Center for International Blood and Marrow Transplant Research's (CIBMTR) Health Services and International Studies Committee have jointly produced an expert opinion statement as a general guide to deal with certain aspects of HCT, including diagnostics for SARS-CoV-2 in HCT recipient, pre- and post-HCT management, donor issues, medical tourism, and facilities management. During these crucial times, which may last for months or years, the HCT community must reorganize to proceed with transplantation activity in those patients who urgently require it, albeit with extreme caution. This shared knowledge may be of value to the HCT community in the absence of high-quality evidence-based medicine. © 2020 American Society for Transplantation and Cellular Therapy. Published by Elsevier Inc.

Topics & Concepts

MedicineHematopoietic cellPandemicCoronavirus disease 2019 (COVID-19)TransplantationBone marrow transplantationHaematopoiesis2019-20 coronavirus outbreakHematopoietic stem cell transplantationBone transplantationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyStem cellInternal medicineSurgeryDiseaseInfectious disease (medical specialty)BiologyGeneticsOutbreakHematopoietic Stem Cell TransplantationCOVID-19 Clinical Research StudiesCOVID-19 and healthcare impacts