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Osimertinib plus savolitinib in patients with EGFR mutation-positive, MET-amplified, non-small-cell lung cancer after progression on EGFR tyrosine kinase inhibitors: interim results from a multicentre, open-label, phase 1b study

Lecia V. Sequist, Ji‐Youn Han, Myung‐Ju Ahn, Byoung Chul Cho, Helena A. Yu, Sang-We Kim, James Chih‐Hsin Yang, Jong Seok Lee, Wu‐Chou Su, Dariusz M. Kowalski, Sergey Orlov, Mireille Cantarini, Remy B. Verheijen, Anders Mellemgaard, Lone H. Ottesen, Paul Frewer, Xiaoling Ou, Geoffrey R. Oxnard

2020The Lancet Oncology413 citationsDOIOpen Access PDF

Topics & Concepts

OsimertinibMedicineInternal medicineLung cancerOncologyTolerabilityInterim analysisClinical endpointTyrosine-kinase inhibitorAdverse effectClinical trialCancerErlotinibEpidermal growth factor receptorLung Cancer Treatments and MutationsFibroblast Growth Factor ResearchLung Cancer Research Studies
Osimertinib plus savolitinib in patients with EGFR mutation-positive, MET-amplified, non-small-cell lung cancer after progression on EGFR tyrosine kinase inhibitors: interim results from a multicentre, open-label, phase 1b study | Litcius