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Repurposing of camptothecin: An esterase-activatable prodrug delivered by a self-emulsifying formulation that improves efficacy in colorectal cancer

Tao Fang, Zhijian Ye, Xiaona Chen, Yuchen Wang, Jianqin Wan, Hangxiang Wang

2021International Journal of Pharmaceutics17 citationsDOI

Topics & Concepts

ProdrugCamptothecinPharmacologyPharmacokineticsIrinotecanDrugActive metaboliteIn vivoChemistryColorectal cancerSN-38BioavailabilityPharmaceutical formulationMedicineCancerBiochemistryBiologyInternal medicineBiotechnologyNanoparticle-Based Drug DeliveryCancer therapeutics and mechanismsNanoplatforms for cancer theranostics
Repurposing of camptothecin: An esterase-activatable prodrug delivered by a self-emulsifying formulation that improves efficacy in colorectal cancer | Litcius