β-Glucan Induces Protective Trained Immunity against Mycobacterium tuberculosis Infection: A Key Role for IL-1
Simone J.C.F.M. Moorlag, Nargis Khan, Boris Novakovic, Eva Kaufmann, Trees Jansen, Reinout van Crevel, Maziar Divangahi, Mihai G. Netea
Abstract
). The administration of β-glucan may be used as a novel strategy in the treatment of mycobacterial infections and possibly as an adjuvant to improve anti-tuberculosis vaccines.
Topics & Concepts
Mycobacterium tuberculosisImmunityMicrobiologyTuberculosisGlucanImmunologyKey (lock)BiologyImmune systemMedicineBiochemistryPathologyEcologyImmune responses and vaccinationsGut microbiota and healthDigestive system and related health