Metal-free, one-pot synthesis of 2-styrylquinolines <i>via</i> Friedländer annulation and sp<sup>3</sup> C–H activation using 1,3-dimethylurea and <scp>l</scp>-tartaric acid (3 : 1) as a deep eutectic solvent
Neeli Satyanarayana, Kota Sathish, Sakkani Nagaraju, Ravinder Pawar, Mohmmad Faizan, Murgan Arumugavel, Thangellapally Shirisha, Dhurke Kashinath
Abstract
Functionalized 2-styrylquinolines are prepared using DMU + l -(+)-tartaric acid as deep eutectic solvent. DFT calculations supported the experimental results on role of DES as catalyst. The absorption-emission spectra indicating that these compounds can be useful as fluorescent probes.
Topics & Concepts
ChemistryTartaric acidAnnulationCatalysisFluorescenceDeep eutectic solventSolventMedicinal chemistryAbsorption spectroscopyEutectic systemPhotochemistryNuclear chemistryOrganic chemistryQuantum mechanicsCitric acidPhysicsAlloyMulticomponent Synthesis of HeterocyclesSynthesis and Biological EvaluationCatalytic C–H Functionalization Methods