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D-Mannose reduces cellular senescence and NLRP3/GasderminD/IL-1β-driven pyroptotic uroepithelial cell shedding in the murine bladder

Chetanchandra S. Joshi, Arnold Salazar, Caihong Wang, Marianne M. Ligon, Rayvanth R. Chappidi, Bisiayo Fashemi, Paul A. Felder, Amy Mora, Sandra L. Grimm, Cristian Coarfa, Indira U. Mysorekar

2023Developmental Cell29 citationsDOIOpen Access PDF

Topics & Concepts

UrotheliumBiologySenescenceOxidative stressAutophagyProteostasisProgrammed cell deathHomeostasisImmunologyCell biologyReactive oxygen speciesInflammasomeInflammationUrinary systemEndocrinologyApoptosisBiochemistryInflammasome and immune disordersUrinary Tract Infections ManagementBladder and Urothelial Cancer Treatments
D-Mannose reduces cellular senescence and NLRP3/GasderminD/IL-1β-driven pyroptotic uroepithelial cell shedding in the murine bladder | Litcius