Hyperferritinemia and the Extent of Mucormycosis in COVID-19 Patients
Simple Bhadania, Neena Bhalodiya, Yashendra Sethi, Nirja Kaka, Swati Mishra, Neil Patel, Asad Ullah Wasim, Saumya Joshi, Kenisha B. Shah
Abstract
Coronavirus disease 2019 (COVID-19) disease attributed to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown associations with various fungal opportunistic infections such as mucormycosis, invasive candidiasis, and aspergillosis, which have contributed to the mortality of the disease. In India, the incidence of mucormycosis had risen rapidly during the second wave. There is ample literature demonstrating the role of iron in the pathogenesis of mucormycosis. The hyperferritinemia associated with COVID-19 may have played a significant role in promoting the invasion and extent of the fungus.