Consumption of dietary turmeric promotes fat browning and thermogenesis in association with gut microbiota regulation in high-fat diet-fed mice
Chengcheng Yang, Yao Du, Tong Zhao, Lu Zhao, Lu Liu, Luyao Liu, Xingbin Yang
Abstract
and production of short-chain fatty acids (SCFAs) and succinate. Interestingly, TP-induced BAT thermogenesis and iWAT browning were highly correlated with the reconstruction of the gut microbiome and formation of SCFAs and succinate. Collectively, these findings manifest beneficial actions of TP on the promotion of adipose browning and thermogenesis in association with gut microbiota reconstruction, and our findings may provide a promising way for preventing obesity.
Topics & Concepts
Gut floraThermogenesisEndocrinologyDysbiosisInternal medicineBiologyDiet-induced obeseBrown adipose tissueObesityAdipose tissueMetabolismMedicineBiochemistryInsulin resistanceAdipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic DiseasesCurcumin's Biomedical Applications