Litcius/Paper detail

Reticular epithelial edema after penetrating keratoplasty in a patient taking netarsudil

Lauren J. Jeang, Ankit S. Shah, Jon D. Hammer, Sonal S. Tuli

2022Digital Journal of Ophthalmology11 citationsDOIOpen Access PDF

Abstract

Netarsudil is a relatively new medication for the treatment of primary open-angle glaucoma and ocular hypertension. It has been associated with red eyes and burning after instillation. Reticular epitheliopathy is a relatively rare complication of netarsudil that has been described in patients with preexisting corneal edema. We report the case of a healthy 76-year-old woman who developed reticular epitheliopathy after full-thickness penetrating keratoplasty that completely resolved following discontinuation of the medication. In cases where netarsudil is initiated for treatment of glaucoma or, off-label, endothelial dysfunction, reticular epithelial edema should be considered in patients complaining of a decline in vision and severe pain.

Topics & Concepts

DiscontinuationMedicineReticular connective tissueEdemaOphthalmologyComplicationOcular hypertensionGlaucomaSurgeryPathologyGlaucoma and retinal disordersProtein Kinase Regulation and GTPase SignalingMultiple Myeloma Research and Treatments
Reticular epithelial edema after penetrating keratoplasty in a patient taking netarsudil | Litcius