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In Vitro Hepatic Uptake in Human and Monkey Hepatocytes in the Presence and Absence of Serum Protein and Its In Vitro to In Vivo Extrapolation

Xiaomin Liang, Yeojin Park, Natalie DeForest, Hao Jia, Xiaofeng Zhao, Congrong Niu, Kelly Wang, Bill J. Smith, Yurong Lai

2020Drug Metabolism and Disposition24 citationsDOIOpen Access PDF

Topics & Concepts

In vitroIn vivoBiologyChemistryBiochemistryPharmacologyGeneticsDrug Transport and Resistance MechanismsLiver Disease Diagnosis and TreatmentLiver physiology and pathology
In Vitro Hepatic Uptake in Human and Monkey Hepatocytes in the Presence and Absence of Serum Protein and Its In Vitro to In Vivo Extrapolation | Litcius