Layer-by-layer construction of zwitterionic/biguanide polymers on silicone rubber as an antifouling and bactericidal coating
Peng Wan, Birong Fan, Youxin Li, Yaning Dong, Weijian Qian, Xiaoxue Ji, Donglin Gan, Pingsheng Liu, Jian Shen
Abstract
-NHSMA) copolymer (SBMA/NHSMA with molar percentage of 70/30) synergistically utilized antifouling and bactericidal abilities to endow a highly efficient overall antibacterial property (near 100% antibacterial ratios) to SR70-PHMB substrates without compromising cellular viability. This strategy may be applied to the many SR-based biomedical implants and devices where an antibacterial surface is required.
Topics & Concepts
BiofoulingBiguanideLayer (electronics)Silicone rubberCoatingMaterials sciencePolymerLayer by layerSiliconeNatural rubberPolymer scienceChemical engineeringComposite materialPolymer chemistryChemistryMembraneBiochemistryMetforminMedicineDiabetes mellitusEndocrinologyEngineeringMarine Biology and Environmental ChemistryAntimicrobial agents and applicationsPolymer Surface Interaction Studies