Rapid, high-yield production of full-length SARS-CoV-2 spike ectodomain by transient gene expression in CHO cells
Matthew Stuible, Christian Gervais, Simon Lord‐Dufour, Sylvie Perret, Denis L’Abbé, Joseph D. Schrag, Gilles St‐Laurent, Yves Durocher
Topics & Concepts
EctodomainSpike (software development)Recombinant DNAChinese hamster ovary cellTransfectionGeneHEK 293 cellsBiologyCell biologyCell cultureMolecular biologyChemistryBiochemistryGeneticsComputer scienceReceptorSoftware engineeringSARS-CoV-2 and COVID-19 ResearchViral Infectious Diseases and Gene Expression in InsectsCRISPR and Genetic Engineering