Neuroprotective Effects of Phlorotannin-Rich Extract from Brown Seaweed Ecklonia cava on Neuronal PC-12 and SH-SY5Y Cells with Oxidative Stress
Jin Ah Nho, Yong Sub Shin, Ha-Ram Jeong, Suengmok Cho, Ho Jin Heo, Gun Hee Kim, Dae‐Ok Kim
Abstract
- and AAPH-induced oxidative damage, partly due to reduced intracellular oxidative stress. PEEC treatment inhibited acetylcholinesterase and butyrylcholinesterase in a dose-dependent manner. Taken together, these findings suggest that PEEC is a good source of antioxidants and neuroprotective materials.
Topics & Concepts
NeuroprotectionOxidative stressSH-SY5YABTSAntioxidantPharmacologyChemistryDPPHBiochemistryMedicineBiologyCell cultureNeuroblastomaGeneticsSeaweed-derived Bioactive CompoundsProtein Hydrolysis and Bioactive PeptidesEchinoderm biology and ecology