CRISPR/Cas9 knock-out of nAChR α6 confers resistance to spinosyns in Frankliniella occidentalis and is associated with a higher fitness cost than target-site mutation G275E
Antonio Mocchetti, Adriana Nikoloudi, John Vontas, Sander De Rouck, Thomas Van Leeuwen
Topics & Concepts
CRISPRBiologyMutationGeneticsResistance (ecology)ToxicologyEcologyGeneInsect-Plant Interactions and ControlInsect and Pesticide ResearchInsect symbiosis and bacterial influences