Phospholipase A <sub>2</sub> inhibitor–loaded micellar nanoparticles attenuate inflammation and mitigate osteoarthritis progression
Yulong Wei, Lesan Yan, Lijun Luo, Tao Gui, Bian Jang, Ahmad Amirshaghaghi, Tianyan You, Andrew Tsourkas, Ling Qin, Zhiliang Cheng
Abstract
i-NPs can be promising therapeutic agents for OA treatment.
Topics & Concepts
OsteoarthritisInflammationNanoparticlePhospholipaseMedicineChemistryCancer researchNanotechnologyMaterials scienceImmunologyBiochemistryPathologyEnzymeAlternative medicineOsteoarthritis Treatment and MechanismsInflammatory mediators and NSAID effectsProtease and Inhibitor Mechanisms