FAEE exerts a protective effect against osteoporosis by regulating the MAPK signalling pathway
Mingyue Wang, Meng‐Fei An, Mao‐Si Fan, Shao-Shi Zhang, Ze‐Rui Sun, Yun‐Li Zhao, Zemin Xiang, Jun Sheng
Abstract
CONTEXT: Hort. (Apiaceae) and grains, and possesses diverse biological activities; but the effects of FAEE on osteoporosis has not been reported. OBJECTIVE: This study investigated whether FAEE can attenuate osteoclastogenesis and relieve ovariectomy-induced osteoporosis via attenuating mitogen-activated protein kinase (MAPK). MATERIALS AND METHODS: , and then histology was undertaken in combination with cytokines analyses. RESULTS: < 0.01). DISCUSSION AND CONCLUSIONS: These findings suggested that FAEE could be used to ameliorate osteoporosis by the MAPK signalling pathway, suggesting that FAEE could be a potential therapeutic candidate for osteoporosis.