Altersolanol B, a fungal tetrahydroanthraquinone, inhibits the proliferation of estrogen receptor-expressing (ER+) human breast adenocarcinoma by modulating PI3K/AKT, p38/ERK MAPK and associated signaling pathways
Md Afjalus Siraj, Aaron T. Jacobs, Ghee Teng Tan
Topics & Concepts
Protein kinase BPI3K/AKT/mTOR pathwayDownregulation and upregulationCancer researchMAPK/ERK pathwaySignal transductionBiologyCell cycle checkpointEstrogen receptorCyclin D1ApoptosisChemistryCell cycleCell biologyCancerBiochemistryBreast cancerGeneGeneticsBioactive Compounds and Antitumor AgentsMorinda citrifolia extract usesCancer Treatment and Pharmacology