Discovery and characterization of small molecule SIRT3-specific inhibitors as revealed by mass spectrometry
Saurabh Loharch, Sonali Chhabra, Abhinit Kumar, Sapna Swarup, Raman Parkesh
Topics & Concepts
SirtuinPharmacophoreChemistrySIRT3Small moleculeDrug discoveryDocking (animal)Computational biologyVirtual screeningBiochemistryIn vitroIn vivoEnzymeBiologyNAD+ kinaseNursingMedicineBiotechnologySirtuins and Resveratrol in MedicineToxin Mechanisms and ImmunotoxinsBiochemical effects in animals