Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A
Sai Kiran Naineni, Jason Liang, Kenneth G. Hull, Regina Cencic, Mingzhao Zhu, Peter T. Northcote, Paul Teesdale‐Spittle, Daniel Romo, Bhushan Nagar, Jerry Pelletier
Topics & Concepts
eIF4ARNAHelicaseEukaryotic translationBiologyRNA Helicase AEukaryotic initiation factorDesmethylStereochemistryTranslation (biology)BiochemistryChemistryNon-coding RNARibosomeMessenger RNAGeneMetaboliteChemical Synthesis and AnalysisRNA and protein synthesis mechanismsPolyamine Metabolism and Applications