Identification of host regulators of Mycobacterium tuberculosis phenotypes uncovers a role for the MMGT1-GPR156 lipid droplet axis in persistence
Haroon Kalam, Chih‐Hung Chou, Motohiko Kadoki, Daniel B. Graham, Jacques Deguine, Deborah T. Hung, Ramnik J. Xavier
Topics & Concepts
BiologyPhenotypeMycobacterium tuberculosisTranscriptomeLipid metabolismLipid dropletGenePersistence (discontinuity)Host (biology)Downregulation and upregulationCell biologyTuberculosisMicrobiologyGeneticsGene expressionBiochemistryGeotechnical engineeringEngineeringMedicinePathologyTuberculosis Research and EpidemiologyCRISPR and Genetic EngineeringBacterial Genetics and Biotechnology