<i>N</i>,<i>N</i>-Diethyl-3-methylbenzamide (DEET) acts as a metal–organic framework synthesis solvent with phase-directing capabilities
Ryan A. Dodson, Andre P. Kalenak, Derek R. Du Bois, Sasha L. Gill-Ljunghammer, Adam J. Matzger
Abstract
Metal-organic frameworks (MOFs) are generally synthesized in toxic formamide solvents. Greener solvents would lower production barriers and facilitate applications such as drug delivery. N,N-Diethyl-3-methylbenzamide (DEET), the most widely used insect repellent, is shown to serve this role. Furthermore, DEET-loaded MOFs can be leveraged in controlled-release insect repellent formulations.
Topics & Concepts
DEETSolventFormamideChemistryPhase (matter)MetalOrganic chemistryToxicologyBiologyMetal-Organic Frameworks: Synthesis and ApplicationsDendrimers and Hyperbranched PolymersCovalent Organic Framework Applications